Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of methods of new drug development The study of mechanisms of drug action The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs Correct! Wrong! - 2. What does “pharmacokinetics” include? Influence of drugs on genes Drug biotransformation in the organism Complications of drug therapy Influence of drugs on metabolism processes Correct! Wrong! - 3. What does “pharmacokinetics” include? Distribution of drugs in the organism Chemical structure of a medicinal agent Unwanted effects of drugs Pharmacological effects of drugs Correct! Wrong! - 4. What does “pharmacokinetics” include? Localization of drug action Interaction of substances Mechanisms of drug action Excretion of substances Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Endocytosis and exocytosis Active transport (carrier-mediated diffusion) Passive diffusion (lipid diffusion) Filtration (aqueous diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Lipid-soluble Hydrophilic substances Non-ionized substances Hydrophobic substances Correct! Wrong! - A hydrophilic medicinal agent has the following property: Easy permeation through the blood-brain barrier High reabsorption in renal tubules Low ability to penetrate through the cell membrane lipids Penetrate through membranes by means of endocytosis Correct! Wrong! - What is implied by «active transport»? Transport of drugs trough a membrane by means of diffusion Transport without energy consumption Engulf of drug by a cell membrane with a new vesicle formation Transport against concentration gradient Correct! Wrong! - What does the term “bio-availability” mean? Amount of a substance in urine relative to the initial doze Fraction of an uncharged drug reaching the systemic circulation following any route administration Permeability through the brain-blood barrier Plasma protein binding degree of substance Correct! Wrong! - The reasons determining bio-availability are: Extent of absorption and hepatic first-pass effect Glomerular filtration rate Rheological parameters of blood Amount of a substance obtained orally and quantity of intakes Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,645 total views, 1 views today
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