Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of methods of new drug development The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs The study of mechanisms of drug action Correct! Wrong! - 2. What does “pharmacokinetics” include? Complications of drug therapy Influence of drugs on genes Drug biotransformation in the organism Influence of drugs on metabolism processes Correct! Wrong! - 3. What does “pharmacokinetics” include? Distribution of drugs in the organism Pharmacological effects of drugs Unwanted effects of drugs Chemical structure of a medicinal agent Correct! Wrong! - 4. What does “pharmacokinetics” include? Interaction of substances Mechanisms of drug action Excretion of substances Localization of drug action Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Filtration (aqueous diffusion) Endocytosis and exocytosis Active transport (carrier-mediated diffusion) Passive diffusion (lipid diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Hydrophobic substances Hydrophilic substances Lipid-soluble Non-ionized substances Correct! Wrong! - A hydrophilic medicinal agent has the following property: Easy permeation through the blood-brain barrier High reabsorption in renal tubules Low ability to penetrate through the cell membrane lipids Penetrate through membranes by means of endocytosis Correct! Wrong! - What is implied by «active transport»? Transport without energy consumption Engulf of drug by a cell membrane with a new vesicle formation Transport of drugs trough a membrane by means of diffusion Transport against concentration gradient Correct! Wrong! - What does the term “bio-availability” mean? Permeability through the brain-blood barrier Amount of a substance in urine relative to the initial doze Fraction of an uncharged drug reaching the systemic circulation following any route administration Plasma protein binding degree of substance Correct! Wrong! - The reasons determining bio-availability are: Rheological parameters of blood Glomerular filtration rate Extent of absorption and hepatic first-pass effect Amount of a substance obtained orally and quantity of intakes Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 2,188 total views, 2 views today
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