Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of biological and therapeutic effects of drugs The study of mechanisms of drug action The study of methods of new drug development The study of absorption, distribution, metabolism and excretion of drugs Correct! Wrong! - 2. What does “pharmacokinetics” include? Drug biotransformation in the organism Influence of drugs on genes Influence of drugs on metabolism processes Complications of drug therapy Correct! Wrong! - 3. What does “pharmacokinetics” include? Distribution of drugs in the organism Pharmacological effects of drugs Chemical structure of a medicinal agent Unwanted effects of drugs Correct! Wrong! - 4. What does “pharmacokinetics” include? Excretion of substances Mechanisms of drug action Interaction of substances Localization of drug action Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Active transport (carrier-mediated diffusion) Filtration (aqueous diffusion) Passive diffusion (lipid diffusion) Endocytosis and exocytosis Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Hydrophilic substances Hydrophobic substances Non-ionized substances Lipid-soluble Correct! Wrong! - A hydrophilic medicinal agent has the following property: Low ability to penetrate through the cell membrane lipids Easy permeation through the blood-brain barrier High reabsorption in renal tubules Penetrate through membranes by means of endocytosis Correct! Wrong! - What is implied by «active transport»? Transport against concentration gradient Engulf of drug by a cell membrane with a new vesicle formation Transport of drugs trough a membrane by means of diffusion Transport without energy consumption Correct! Wrong! - What does the term “bio-availability” mean? Amount of a substance in urine relative to the initial doze Plasma protein binding degree of substance Fraction of an uncharged drug reaching the systemic circulation following any route administration Permeability through the brain-blood barrier Correct! Wrong! - The reasons determining bio-availability are: Rheological parameters of blood Extent of absorption and hepatic first-pass effect Glomerular filtration rate Amount of a substance obtained orally and quantity of intakes Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,443 total views, 1 views today
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