Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of mechanisms of drug action The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs The study of methods of new drug development Correct! Wrong! - 2. What does “pharmacokinetics” include? Influence of drugs on genes Complications of drug therapy Drug biotransformation in the organism Influence of drugs on metabolism processes Correct! Wrong! - 3. What does “pharmacokinetics” include? Unwanted effects of drugs Pharmacological effects of drugs Distribution of drugs in the organism Chemical structure of a medicinal agent Correct! Wrong! - 4. What does “pharmacokinetics” include? Excretion of substances Interaction of substances Mechanisms of drug action Localization of drug action Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Endocytosis and exocytosis Filtration (aqueous diffusion) Active transport (carrier-mediated diffusion) Passive diffusion (lipid diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Hydrophilic substances Hydrophobic substances Non-ionized substances Lipid-soluble Correct! Wrong! - A hydrophilic medicinal agent has the following property: Low ability to penetrate through the cell membrane lipids Easy permeation through the blood-brain barrier High reabsorption in renal tubules Penetrate through membranes by means of endocytosis Correct! Wrong! - What is implied by «active transport»? Transport against concentration gradient Transport without energy consumption Transport of drugs trough a membrane by means of diffusion Engulf of drug by a cell membrane with a new vesicle formation Correct! Wrong! - What does the term “bio-availability” mean? Plasma protein binding degree of substance Permeability through the brain-blood barrier Amount of a substance in urine relative to the initial doze Fraction of an uncharged drug reaching the systemic circulation following any route administration Correct! Wrong! - The reasons determining bio-availability are: Glomerular filtration rate Rheological parameters of blood Extent of absorption and hepatic first-pass effect Amount of a substance obtained orally and quantity of intakes Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,916 total views, 9 views today
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