Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of absorption, distribution, metabolism and excretion of drugs The study of mechanisms of drug action The study of methods of new drug development The study of biological and therapeutic effects of drugs Correct! Wrong! - 2. What does “pharmacokinetics” include? Influence of drugs on metabolism processes Complications of drug therapy Influence of drugs on genes Drug biotransformation in the organism Correct! Wrong! - 3. What does “pharmacokinetics” include? Chemical structure of a medicinal agent Pharmacological effects of drugs Unwanted effects of drugs Distribution of drugs in the organism Correct! Wrong! - 4. What does “pharmacokinetics” include? Interaction of substances Localization of drug action Excretion of substances Mechanisms of drug action Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Active transport (carrier-mediated diffusion) Endocytosis and exocytosis Passive diffusion (lipid diffusion) Filtration (aqueous diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Non-ionized substances Hydrophobic substances Hydrophilic substances Lipid-soluble Correct! Wrong! - A hydrophilic medicinal agent has the following property: High reabsorption in renal tubules Penetrate through membranes by means of endocytosis Low ability to penetrate through the cell membrane lipids Easy permeation through the blood-brain barrier Correct! Wrong! - What is implied by «active transport»? Transport without energy consumption Transport of drugs trough a membrane by means of diffusion Transport against concentration gradient Engulf of drug by a cell membrane with a new vesicle formation Correct! Wrong! - What does the term “bio-availability” mean? Amount of a substance in urine relative to the initial doze Permeability through the brain-blood barrier Fraction of an uncharged drug reaching the systemic circulation following any route administration Plasma protein binding degree of substance Correct! Wrong! - The reasons determining bio-availability are: Rheological parameters of blood Amount of a substance obtained orally and quantity of intakes Extent of absorption and hepatic first-pass effect Glomerular filtration rate Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,486 total views, 1 views today
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