Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of absorption, distribution, metabolism and excretion of drugs The study of mechanisms of drug action The study of methods of new drug development The study of biological and therapeutic effects of drugs Correct! Wrong! - 2. What does “pharmacokinetics” include? Drug biotransformation in the organism Influence of drugs on genes Influence of drugs on metabolism processes Complications of drug therapy Correct! Wrong! - 3. What does “pharmacokinetics” include? Chemical structure of a medicinal agent Unwanted effects of drugs Distribution of drugs in the organism Pharmacological effects of drugs Correct! Wrong! - 4. What does “pharmacokinetics” include? Mechanisms of drug action Interaction of substances Localization of drug action Excretion of substances Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Filtration (aqueous diffusion) Endocytosis and exocytosis Passive diffusion (lipid diffusion) Active transport (carrier-mediated diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Hydrophilic substances Non-ionized substances Hydrophobic substances Lipid-soluble Correct! Wrong! - A hydrophilic medicinal agent has the following property: Low ability to penetrate through the cell membrane lipids High reabsorption in renal tubules Penetrate through membranes by means of endocytosis Easy permeation through the blood-brain barrier Correct! Wrong! - What is implied by «active transport»? Engulf of drug by a cell membrane with a new vesicle formation Transport without energy consumption Transport of drugs trough a membrane by means of diffusion Transport against concentration gradient Correct! Wrong! - What does the term “bio-availability” mean? Fraction of an uncharged drug reaching the systemic circulation following any route administration Permeability through the brain-blood barrier Amount of a substance in urine relative to the initial doze Plasma protein binding degree of substance Correct! Wrong! - The reasons determining bio-availability are: Glomerular filtration rate Rheological parameters of blood Amount of a substance obtained orally and quantity of intakes Extent of absorption and hepatic first-pass effect Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,794 total views, 4 views today
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