Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of methods of new drug development The study of absorption, distribution, metabolism and excretion of drugs The study of mechanisms of drug action The study of biological and therapeutic effects of drugs Correct!Wrong!-2. What does “pharmacokinetics” include? Drug biotransformation in the organism Influence of drugs on genes Complications of drug therapy Influence of drugs on metabolism processes Correct!Wrong!-3. What does “pharmacokinetics” include? Distribution of drugs in the organism Chemical structure of a medicinal agent Unwanted effects of drugs Pharmacological effects of drugs Correct!Wrong!-4. What does “pharmacokinetics” include? Interaction of substances Localization of drug action Excretion of substances Mechanisms of drug action Correct!Wrong!-The main mechanism of most drugs absorption in GI tract is Passive diffusion (lipid diffusion) Active transport (carrier-mediated diffusion) Filtration (aqueous diffusion) Endocytosis and exocytosis Correct!Wrong!-What kind of substances can’t permeate membranes by passive diffusion? Hydrophobic substances Lipid-soluble Non-ionized substances Hydrophilic substances Correct!Wrong!-A hydrophilic medicinal agent has the following property: Low ability to penetrate through the cell membrane lipids Easy permeation through the blood-brain barrier Penetrate through membranes by means of endocytosis High reabsorption in renal tubules Correct!Wrong!-What is implied by «active transport»? Engulf of drug by a cell membrane with a new vesicle formation Transport against concentration gradient Transport without energy consumption Transport of drugs trough a membrane by means of diffusion Correct!Wrong!-What does the term “bio-availability” mean? Permeability through the brain-blood barrier Fraction of an uncharged drug reaching the systemic circulation following any route administration Plasma protein binding degree of substance Amount of a substance in urine relative to the initial doze Correct!Wrong!-The reasons determining bio-availability are: Glomerular filtration rate Rheological parameters of blood Amount of a substance obtained orally and quantity of intakes Extent of absorption and hepatic first-pass effect Correct!Wrong!- Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 2,778 total views, 1 views today
