Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of methods of new drug development The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs The study of mechanisms of drug action Correct! Wrong! - 2. What does “pharmacokinetics” include? Drug biotransformation in the organism Influence of drugs on genes Influence of drugs on metabolism processes Complications of drug therapy Correct! Wrong! - 3. What does “pharmacokinetics” include? Unwanted effects of drugs Chemical structure of a medicinal agent Pharmacological effects of drugs Distribution of drugs in the organism Correct! Wrong! - 4. What does “pharmacokinetics” include? Localization of drug action Excretion of substances Mechanisms of drug action Interaction of substances Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Endocytosis and exocytosis Active transport (carrier-mediated diffusion) Filtration (aqueous diffusion) Passive diffusion (lipid diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Non-ionized substances Lipid-soluble Hydrophobic substances Hydrophilic substances Correct! Wrong! - A hydrophilic medicinal agent has the following property: Easy permeation through the blood-brain barrier Low ability to penetrate through the cell membrane lipids Penetrate through membranes by means of endocytosis High reabsorption in renal tubules Correct! Wrong! - What is implied by «active transport»? Transport of drugs trough a membrane by means of diffusion Engulf of drug by a cell membrane with a new vesicle formation Transport against concentration gradient Transport without energy consumption Correct! Wrong! - What does the term “bio-availability” mean? Fraction of an uncharged drug reaching the systemic circulation following any route administration Amount of a substance in urine relative to the initial doze Permeability through the brain-blood barrier Plasma protein binding degree of substance Correct! Wrong! - The reasons determining bio-availability are: Amount of a substance obtained orally and quantity of intakes Extent of absorption and hepatic first-pass effect Glomerular filtration rate Rheological parameters of blood Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,481 total views, 1 views today
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