Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of mechanisms of drug action The study of methods of new drug development The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs Correct! Wrong! - 2. What does “pharmacokinetics” include? Influence of drugs on genes Drug biotransformation in the organism Influence of drugs on metabolism processes Complications of drug therapy Correct! Wrong! - 3. What does “pharmacokinetics” include? Pharmacological effects of drugs Distribution of drugs in the organism Unwanted effects of drugs Chemical structure of a medicinal agent Correct! Wrong! - 4. What does “pharmacokinetics” include? Excretion of substances Localization of drug action Mechanisms of drug action Interaction of substances Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Filtration (aqueous diffusion) Passive diffusion (lipid diffusion) Endocytosis and exocytosis Active transport (carrier-mediated diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Non-ionized substances Hydrophilic substances Hydrophobic substances Lipid-soluble Correct! Wrong! - A hydrophilic medicinal agent has the following property: Low ability to penetrate through the cell membrane lipids Penetrate through membranes by means of endocytosis Easy permeation through the blood-brain barrier High reabsorption in renal tubules Correct! Wrong! - What is implied by «active transport»? Transport against concentration gradient Transport without energy consumption Transport of drugs trough a membrane by means of diffusion Engulf of drug by a cell membrane with a new vesicle formation Correct! Wrong! - What does the term “bio-availability” mean? Fraction of an uncharged drug reaching the systemic circulation following any route administration Permeability through the brain-blood barrier Plasma protein binding degree of substance Amount of a substance in urine relative to the initial doze Correct! Wrong! - The reasons determining bio-availability are: Rheological parameters of blood Amount of a substance obtained orally and quantity of intakes Glomerular filtration rate Extent of absorption and hepatic first-pass effect Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,462 total views, 1 views today
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