Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs The study of mechanisms of drug action The study of methods of new drug development Correct! Wrong! - 2. What does “pharmacokinetics” include? Drug biotransformation in the organism Influence of drugs on genes Complications of drug therapy Influence of drugs on metabolism processes Correct! Wrong! - 3. What does “pharmacokinetics” include? Chemical structure of a medicinal agent Pharmacological effects of drugs Unwanted effects of drugs Distribution of drugs in the organism Correct! Wrong! - 4. What does “pharmacokinetics” include? Mechanisms of drug action Excretion of substances Localization of drug action Interaction of substances Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Filtration (aqueous diffusion) Endocytosis and exocytosis Passive diffusion (lipid diffusion) Active transport (carrier-mediated diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Non-ionized substances Lipid-soluble Hydrophilic substances Hydrophobic substances Correct! Wrong! - A hydrophilic medicinal agent has the following property: Easy permeation through the blood-brain barrier High reabsorption in renal tubules Penetrate through membranes by means of endocytosis Low ability to penetrate through the cell membrane lipids Correct! Wrong! - What is implied by «active transport»? Transport against concentration gradient Transport of drugs trough a membrane by means of diffusion Engulf of drug by a cell membrane with a new vesicle formation Transport without energy consumption Correct! Wrong! - What does the term “bio-availability” mean? Plasma protein binding degree of substance Fraction of an uncharged drug reaching the systemic circulation following any route administration Amount of a substance in urine relative to the initial doze Permeability through the brain-blood barrier Correct! Wrong! - The reasons determining bio-availability are: Rheological parameters of blood Glomerular filtration rate Amount of a substance obtained orally and quantity of intakes Extent of absorption and hepatic first-pass effect Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,506 total views, 1 views today
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