Basic Pharmacology Quiz – Part 1 Test your basic pharmacology knowledge – Level : Easy 1. Pharmacokinetics is: The study of methods of new drug development The study of mechanisms of drug action The study of absorption, distribution, metabolism and excretion of drugs The study of biological and therapeutic effects of drugs Correct! Wrong! - 2. What does “pharmacokinetics” include? Complications of drug therapy Drug biotransformation in the organism Influence of drugs on genes Influence of drugs on metabolism processes Correct! Wrong! - 3. What does “pharmacokinetics” include? Distribution of drugs in the organism Pharmacological effects of drugs Chemical structure of a medicinal agent Unwanted effects of drugs Correct! Wrong! - 4. What does “pharmacokinetics” include? Mechanisms of drug action Interaction of substances Localization of drug action Excretion of substances Correct! Wrong! - The main mechanism of most drugs absorption in GI tract is Endocytosis and exocytosis Active transport (carrier-mediated diffusion) Passive diffusion (lipid diffusion) Filtration (aqueous diffusion) Correct! Wrong! - What kind of substances can’t permeate membranes by passive diffusion? Non-ionized substances Hydrophilic substances Hydrophobic substances Lipid-soluble Correct! Wrong! - A hydrophilic medicinal agent has the following property: High reabsorption in renal tubules Low ability to penetrate through the cell membrane lipids Easy permeation through the blood-brain barrier Penetrate through membranes by means of endocytosis Correct! Wrong! - What is implied by «active transport»? Transport without energy consumption Transport against concentration gradient Transport of drugs trough a membrane by means of diffusion Engulf of drug by a cell membrane with a new vesicle formation Correct! Wrong! - What does the term “bio-availability” mean? Amount of a substance in urine relative to the initial doze Permeability through the brain-blood barrier Plasma protein binding degree of substance Fraction of an uncharged drug reaching the systemic circulation following any route administration Correct! Wrong! - The reasons determining bio-availability are: Glomerular filtration rate Amount of a substance obtained orally and quantity of intakes Rheological parameters of blood Extent of absorption and hepatic first-pass effect Correct! Wrong! - Share the quiz to show your results ! Facebook Facebook Just tell us who you are to view your results ! Your first name : Your e-mail address : Show my results >> Ignore & see my results >> Basic Pharmacology Score : %%score%% of %%total%% right Share your results Facebook Facebook Twitter Google+ 1,518 total views, 1 views today
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