Paracetamol (acetaminophenol) is the most famous Antipyretic on earth
it’s much more safe than aspirin ,
used for Children , Pregnant women , Patients with hyper-acidity Or using anticogulants
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Recommended daily dose : 2000 mgs
Not TONS !! ,.. tons are just for dragons !!
in fact, Large doses cause Nausea , Vomiting , Diarrhea
& also it causes severe hepato-toxicity + central lobular necrosis
Due to the formation of toxic metabolite “NAPQI”
Hint : Ingestion of 15 gms of paracetamol could be fatal
What is the Antidote of Paracetamol Toxicity?
It is N–Acetyl Cysteine (Nac)
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Reference : ” Basic and Clinical Pharmacology ” \\ chapter 35 \\ page 444