Drug facts

List of teratogenic drugs that should be avoided

A lot of drugs have side effects or undesired actions beside its therapeutic effect. Teratogenic drugs are those which exploit the fetus and definitely should be avoided in pregnancy.

below down the most common teratogenic drugs and their effects:

Drug Effect


phocomelia and multiple defects

Anticancer drugs

cleft palate, hydrocephalus, multiple defects and foetal death


virilization; limb, esophageal, cardiac defects


virilization of female foetus


vaginal carcinoma in teenage female offspring

Tetracyclines & Glycylcyclines

discolored and deformed teeth, retarded bone growth


depressed nose; eye and hand defects, growth retardation


hypoplastic phalanges, cleft lip/palate, microcephaly


various malformations


neural tube defects, other abnormalities


spina bifida and other neural tube defects


low IQ baby, growth retardation, fetal alcohol syndrome

ACE inhibitors

hypoplasia of organs, growth retardation, fetal loss

fetal goiter, cardiac and other abnormalities


premature closure of ductus arteriosus


craniofacial, heart and CNS defects


Once you become pregnant, or even when you plan for pregnancy you have to consult a pharmacist or physician about every single medication and read the insert leaflet carefully to avoid any harm to you or your fetus.

FDA has a specific classification for drug labeling during pregnancy:

This is a good website to check any medication for your baby safety: http://www.safefetus.com/

Again and Again, you have to consult a health care professional with your case before using any medication whatever it is during your pregnancy.


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