SSRI VS SNRI
Serotonin and norepinephrine reuptake inhibitors (SNRI)
SNRI manage depression associated with pain. This is attributed to their ability to inhibit the reuptake of norepinephrine.
Selective serotonin reuptake inhibitors (SSRI)
Combining antidepressant medications from different classes like SNRI,SSRI and TCAs could lead to Serotonin Syndrome.
Also other drugs like Linezolid & Fentanyl could cause the Serotonin Syndrome if combined with the above classes.
Serotonin Syndrome is a serious medical condition. We will assign another post to discuss it.