Top 10 pharmaceutical products in 2023 with MoA – ranked!

This following list has the top 10 drugs that have the potential to be game-changers in the field of medicine and provide new hope for patients with serious diseases.

They are ranked by the projected USD sales in billions.

DrugCompanyDiseaseProjected sales (billion USD)Mechanism of action
KeytrudaMerck & Co.Cancer24Immunotherapy drug that blocks the PD-1 protein, which helps cancer cells evade the immune system.
Comirnaty/Covid-19 vaccinePfizerCOVID-1919Vaccine that uses mRNA technology to teach the body’s cells how to make the spike protein from the SARS-CoV-2 virus.
HumiraAbbVieRheumatoid arthritis, autoimmune diseases13.5Biologic drug that blocks the activity of tumor necrosis factor-alpha (TNF-α), a protein that causes inflammation.
PaxlovidPfizerCOVID-1913Antiviral drug that blocks the activity of the SARS-CoV-2 virus’s RNA-dependent RNA polymerase enzyme, which is essential for the virus to replicate.
DupixentSanofiAtopic dermatitis, allergic conditions12Biologic drug that blocks the activity of the IL-4 and IL-13 proteins, which are involved in the development of allergic reactions.
RituxanGenentechNon-Hodgkin’s lymphoma, other cancers11Biologic drug that targets and destroys B cells, a type of white blood cell that can become cancerous.
StelaraJanssenPsoriasis, ulcerative colitis10Biologic drug that blocks the activity of the IL-12 and IL-23 proteins, which are involved in the development of psoriasis and ulcerative colitis.
SpinrazaBiogenSpinal muscular atrophy9Injectable drug that delivers a gene into the spinal cord to help produce a protein that is essential for muscle function.
GleevecNovartisChronic myeloid leukemia, other cancers8Targeted therapy drug that blocks the activity of the BCR-ABL protein, which is found in cells with chronic myeloid leukemia.
AvastinGenentechCancer7Anti-angiogenesis drug that blocks the growth of new blood vessels, which are needed by tumors to grow.
0 0 votes
Article Rating
Notify of
Inline Feedbacks
View all comments
Would love your thoughts, please comment.x